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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80cc22b38af835aaa82abcd61b66801ac5dbb1fef10ef677439c62f0343c58db' 
  AND token = 'dwsVrT4tZR0rzRiRcQ5ft3Rc2R6RJ7b65Zo56PlBTdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}