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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9099def3f577785f94e92dfa46fb4b37720a8a7ff6adbb5167d797990e509f10' 
  AND token = 'iFSMW7Opg8w2QcWjfbdWT2xhpmpi+zGjzXjyLFdvoEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}