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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3999361c52b92b2acec0e48f141da3fdfef2d7c526d8a22b16fd78f22391ac5c' 
  AND token = 'YjlEZdlDRr1UrLkYbL0hndE3aKKC8sK+2gRTNSbWQP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}