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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0634b52e665ba83f4ecd43e848b05b52d3bb049ab4aace57ac042286d5cccfa' 
  AND token = 'ueErPSD2FeDGKu68kuIpnWGTPomNhvoDWm5Dq15KIOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}