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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f7eda1d267c2592422ad49a79cb1535ccb8e48c49337c25a7a57c2646de662f' 
  AND token = 'rTpaSd7424Sr/CB42W+LwzPorLet13Mj1WQGKhdoH8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}