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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '703c9f480f38f581466fc2fc6965787812cb15175818eb808e2bcf6de98da598' 
  AND token = '+SGyMzgVU+mo2Dqhle0aV/kEM7WjAhnrrKfhUSTMM4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}