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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb88467a89bd682fa6ce5dce8a779b1b629ab24bd645d514fbfe923a0c64c560' 
  AND token = '2mAjmsg9nkbWzXwTxeedHuFVzSu0v9for05ZsZMgjfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}