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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5922014e79cf40b38423a4e1e383593553b58c2914e1e282f66d5fa3e1e372ed' 
  AND token = 'j40Jqtx8NEYY+bts1L2TPlFQM5NCqF2uh2ptRVIy7x0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}