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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cb01baa2fda042eda9c3bc7b247a14df30c7e434469b0fe5da0aa4261f94a1d' 
  AND token = 'iqbXnMYnUh3xlBLn8Z/3cktIkidPO08AQzxRYnIn4Nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}