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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f818dd35b52c9d40cb8df7de45274fd36a088166806bc2ac95263fc31356986' 
  AND token = 'eTGmn4iE1gd2SUYmkifpL3++i7/U0hWDEebegV/+FYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}