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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f38d6d22f2b9dc9b5186b9a64a255abfffa56ea61349b909cc4fa33539eeff3' 
  AND token = 'ICWxLS0QgZKLobW5Fo/ZyMQgK/GOMwRYwdo4ysqClKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}