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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c825f301e5803f959c1fc1d98c2efb73bed72686190f05611120181884d4ed1f' 
  AND token = 'sHG1x/ufK7jqf4IXFyG1GLcewPzaYFEs4aOhCeZMnWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}