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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '305735c3e380e83f03fe866016f0007d29b9d6a0f985e75eb4d6a4ac56fbbabd' 
  AND token = 'C3H6YjkM7osiSFy8EQvHa8BBZtltOwmE1EZLvEzTAkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}