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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ca3de4795260f681ecf10aab46d9f3d2b0a0954b80c425a5026b311640b4786' 
  AND token = '0PLK8O5/b++1qXW22bKVQjDj4eUa/wV6Dx8bqOs0p/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}