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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e10f93e599f8f17ff75e53c4ba34a8b88c5c46f3c2850432d2f4de4a20091d03' 
  AND token = 'euE/l7w69GcfbfkaHHdipnYlaVPNXmVkh5Y6MKN/Lk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}