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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8ecea923c8c46aa1e922630ce5d9edf7ab5fc46d5033cc3588e51e5b6ae9cd4' 
  AND token = 'gMldFzlxJlT0SiNgbaM8Sn2uaWU8N27+jUUM5ZWDXsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}