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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fb210596d41fb74bac7767e4da5624b270c4d6a67bb37e2f68c6b684158a6a2' 
  AND token = '/+ryC/xQZBTmL1/7E5g5Ga5W9Pepb5pMevfsbdv/FWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}