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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecf4264778baf5d81174890e8372c3eb345c3e8dca7aacd3e77a1e351718b6f4' 
  AND token = 'yrVtDAC7uUAPykm6nRHZXzvSe2mqT4hFkzLB1gGwSlk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}