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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea5f4da367c1ce0c8996c4308f557b093de7226b1e900b68a27a37da50cedc1d' 
  AND token = 'DW/NCGXM/u96nO0LpmJlv3TCOJm6R82QqZQxkNiX3hA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}