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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8e9691c22c3d2a86599dac04f111bc692c2d3b55a5fcb406d21a38bc919af7a' 
  AND token = '/jxnS8SbSKeXKSsg5gQd3f6eZsl7DLExPiETAIq/FyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}