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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd75eabc458ad9391ae01173d8a5cdc387fc6bd1daf28d236cab823d1ff406e7' 
  AND token = 'A2YKnyn7Xxev1PHUYUA7IQUYCgrDvu4bjznHCMNCA7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}