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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e217cae8aad1b1a8fb61477050f06b69091e97369b8ed5b20c69d417a07f27a2' 
  AND token = 'x6ndC596hNqNcETfxJ0VJBV65fsYQR2zaybuTN2mWSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}