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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fe68c698d6abcf710a6e239808a64b3818d16692ab39fd9fc40b2ba77c9b8e4' 
  AND token = 'E/msDWRe/vQA7E9fT+9vu5bGa3QZgaCjzPlKzO1l6I0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}