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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f5738af7c056daeb5ef78b4f144517a64d8c10a0734df8db9f26b17dd2b899e' 
  AND token = 'KfkJHK8BikD9MFKLbd2oUiEFHjAcIZ+XbtKaFtMz4Gg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}