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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ea8f4d9279f3bb72c6b90e6a5eca7429d8c9b25a2654ac66c0b87d692fa76d0' 
  AND token = 'pI55XYOxyv2i+YaOXMGJa5fLj+ZB90QzGFAHTrsx78A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}