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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8e104e75ce0457fd3730ff2b575292da3d41a6046e8a67bd1f21c60673e12e0' 
  AND token = 'jFyXUnQG5hYkhhDT9trEQExoi+FTawPVZ1iqASS7zkw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}