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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52de8b0d08f7d53fc0207a6cba048ae55e9d6227652178c0604e404259b5f59b' 
  AND token = 'k21oudkwDUG4ywaAm2G/0zX0cYIQ1pGXotcapfoNLfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}