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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05f32c8fcb5315297a352d9983c0a2791d540e5cfdfa4572658cfc9155e5f2bc' 
  AND token = 'DYE/c1Ng9XLrcx2ytMC7SimGTgMfsrxsU9U3+FJeaUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}