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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4997890ee96eb61202da28c1759c97fe43b7ea81881d8f88223c0dedb05f7e29' 
  AND token = 'BvfjyrY6aM1/1I+N1rqiOr6SddH0jV0qgmyhkG6N6QU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}