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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da61f7e1371d0511b155207dc24915711cd503399dba00e3a0ee989595863423' 
  AND token = 'WaAffLb8ruuhwpst9Wdegj7YR2iu+VosiKMRtSoiRdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}