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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eaeb4f93d5004f4c18044ac8f66c430ae406fc8866a4eca94207d113e49a331d' 
  AND token = 'lMNaZH+AniHlkNfl1paXFlCQFdtuPSd5ZmZWacj2bYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}