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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7d9b4e731c6bd21b3301032ba4e40d863756d477a3a2fefc201ff3cad32e0c3' 
  AND token = 'JdOr0uO49anPrRWa2rWgxDILGznF3+63Lt7DBXz+Vy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}