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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7250e51a8b7344694fca1c62c4870a714598a7acae46a9376c712827913c0a36' 
  AND token = 'n4Hb1g3RtLUKDy8NHH5TOOxmacj1VCnP6tqz2tAvfrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}