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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33d72256924a43d9a81657499ab76ab9143f36cd5e9be42fcb5199dfcee1b6d3' 
  AND token = '/cyNS4Q/BJhTksGw1EZ7kkSiucL9amq28PRvPgLbMSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}