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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb2f2ac12a757a51a7fe7b10233d00dfabcb3406dfed4cc81da44d6f2ebf3491' 
  AND token = '3/vdCEaA5uBLDZBvMCT6jmjhBHQjg0EmtlHVCfX2Nqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}