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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3541ba78a7c0458dc357baffc32675b55451ce7befdf58a502837f3a83d798ba' 
  AND token = 'nJsbZBEJjlIy2+/V7XHOHGeBahHOAQ1tsrFMonDj6cw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}