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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa19f7b4b5e31b45c6301ce47b5553f30ae99567ff7b2821456a84529216e7ed' 
  AND token = 'i4M16AsRx+8hxSqx/lQzGWnQWwASznb9cv5GCN4d+rA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}