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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de5f54156e0c45231e49207e381e92aa2a065e8cc08d15a033e186cb147c597c' 
  AND token = 'gw0glDC+4LSng2bRFbG7K11oIjB9KAHsfO1wCoSJ/DE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}