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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1dc95ac7572369150958ee85e9c526d4054a03491be683bcee41545389ed9676' 
  AND token = 'qp4EEDPUaeMuwNzlGO3mFLSRLQzeAqecV5RGQFdj3PQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}