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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '743ca93c7e57377339d249de2026fdc87399e34affbda374b258c1a71a78378d' 
  AND token = 'laW5uac82qvqdvQfA56GnB+LnXKCKiz3empTEx0Y66s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}