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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '484d2b3cde8eff4c435b34c087d978ee6b0715942bf0446dffe5936dab85278a' 
  AND token = 'JBnyUAK5qL+e1mhVo6kd2tM1zK1OvoYfHaPNv07Trew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}