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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b0582dd91ada82568d8a7c845eaa4ffcda8f77415436616fcedd62af3e6142a' 
  AND token = 'KsnyR5qmje/AGCi9HntfEIumzI5IBeEbns8vuKjDNps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}