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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1aed3ad62db1a93fb3c5a77661d7c9d96c10d10b1940b3de1b5b4ccadfe314d5' 
  AND token = 'JLx82xPB6sheQ2OMfe2wqGNOQWFbblmz571QTx9gnCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}