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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e040f36de3c95eceb5f8f815710c4087748272f2dbb7bc1e1ad024ccecdd5da' 
  AND token = 'OkHIuuWqdAL3rmkOrZJvNccUD4p444FcLd1kq9VLpSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}