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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd22c4b155748ed0f3a9c7f5226c29c6f37f173ce0621f499d3db802f193c9374' 
  AND token = '9DrKsdMFvAr9WLDQkomXiR8LkD8zPsiLYdYd0T0TQfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}