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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2ce7f3d8da8f5172bd3a1c848f8486380831f100db487fd785f80b75243b870' 
  AND token = 'D9ossYbCk1JsRmCYjHrTFQzmsPFNftmo5IQyTbFky6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}