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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5aa27587a71114e9eb12d0be4e31d4807686814038946db5f7418c79e31bf0d' 
  AND token = '81VVi8iqUvuWn3maaLpbE8Q8UkZhMMi4f/9n+nDFvEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}