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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e38d359628fb797b8d9114deaefde78aeea2f6977c3c37e8f597190160f80b96' 
  AND token = 'S41lG3lngL5Qn+qlVDxxQ4BokZM+jABr1jtbxl1iDrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}