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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25b581a2964d59316378327298fdad7a93bf1c260a3a11579549ca99a7f3438b' 
  AND token = '8ymNdHS0Ezg+RIh+dw3oWDFt3A6b7EWuIKK1IF33PGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}