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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a9d1c2c9863e9f819a968ffbb074acc7846932977cdd9a313943e7eb2e52e07' 
  AND token = 'wPXnihEZVlBg2T4NiaieCRK9alADlsa4oMzVLMF1gjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}